Does the driver list your cfg file when hovering over the 3Dx systray icon while your game is in focus?
Turning on the log file will give you a lot of information about how the cfg files are chosen for the application.
This is done in the 3Dx systray icon menu.The file is %localappdata%/3Dconnexion/3DxWare/3DxService.log.
We had some very good luck with joystick emulation with Steam games (played Portal a lot) when we first wrote this driver.
Forum user Hypersonic reconfigured the game cfg a bit to make it work, but it was almost as good as native support.
I did not find the right solution from the internet.
References:http://www.3dconnexion.com/forum/viewtopic.php?t=19373Explainer Video Production Company